:root{--primary-h:212;--primary-s:100%;--primary-l:48%;--primary:hsl(var(--primary-h), var(--primary-s), var(--primary-l));--primary-hover:hsl(var(--primary-h), var(--primary-s), 40%);--primary-light:hsl(var(--primary-h), var(--primary-s), 96%);--primary-subtle:hsl(var(--primary-h), var(--primary-s), 92%);--secondary:#06b6d4;--accent:#ff477e;--accent-light:#fff0f4;--bg-primary:#f8fafc;--bg-secondary:#fff;--bg-tertiary:#f1f5f9;--bg-card:#fff;--text-primary:#0f172a;--text-secondary:#475569;--text-muted:#94a3b8;--border-color:#e2e8f0;--border-highlight:#cbd5e1;--success:#10b981;--success-bg:#ecfdf5;--warning:#f59e0b;--warning-bg:#fffbeb;--danger:#ef4444;--danger-bg:#fef2f2;--gradient-hero:linear-gradient(135deg, #0284c7 0%, #06b6d4 50%, #3b82f6 100%);--gradient-card:linear-gradient(180deg, #fff 0%, #f8fafc 100%);--gradient-accent:linear-gradient(135deg, #ff477e 0%, #ff758c 100%);--gradient-pipette:linear-gradient(180deg, #06b6d4cc 0%, #0284c7f2 100%);--font-main:"Plus Jakarta Sans", system-ui, -apple-system, sans-serif;--font-heading:"Outfit", var(--font-main);--shadow-sm:0 1px 2px 0 #0f172a0d;--shadow-md:0 4px 6px -1px #0f172a14, 0 2px 4px -2px #0f172a0a;--shadow-lg:0 10px 25px -5px #0f172a1a, 0 8px 10px -6px #0f172a0a;--shadow-glow:0 0 25px #0284c740;--shadow-inner:inset 0 2px 4px 0 #0000000f;--radius-sm:8px;--radius-md:12px;--radius-lg:18px;--radius-xl:24px;--radius-full:9999px;--transition-fast:.15s ease;--transition-normal:.25s cubic-bezier(.4, 0, .2, 1);--transition-bounce:.4s cubic-bezier(.34, 1.56, .64, 1)}[data-theme=dark]{--bg-primary:#0f172a;--bg-secondary:#1e293b;--bg-tertiary:#334155;--bg-card:#1e293b;--text-primary:#f8fafc;--text-secondary:#cbd5e1;--text-muted:#64748b;--border-color:#334155;--border-highlight:#475569;--primary-light:#0284c726;--accent-light:#ff477e26;--gradient-card:linear-gradient(180deg, #1e293b 0%, #0f172a 100%);--shadow-sm:0 1px 2px 0 #0000004d;--shadow-md:0 4px 12px #00000059;--shadow-lg:0 12px 30px #00000073;--shadow-glow:0 0 30px #06b6d44d}*,:before,:after{box-sizing:border-box;margin:0;padding:0}html{scroll-behavior:smooth;-webkit-font-smoothing:antialiased;font-size:16px}body{font-family:var(--font-main);background-color:var(--bg-primary);color:var(--text-primary);min-height:100vh;transition:background-color var(--transition-normal), color var(--transition-normal);line-height:1.6;overflow-x:hidden}h1,h2,h3,h4,h5,h6{font-family:var(--font-heading);color:var(--text-primary);font-weight:700;line-height:1.25}a{color:var(--primary);transition:color var(--transition-fast);text-decoration:none}a:hover{color:var(--primary-hover)}button{font-family:var(--font-main);cursor:pointer;background:0 0;border:none;outline:none}input,select{font-family:var(--font-main)}.container{width:100%;max-width:1200px;margin:0 auto;padding:0 1.25rem}.section-padding{padding:3.5rem 0}.site-header{z-index:100;-webkit-backdrop-filter:blur(12px);border-bottom:1px solid var(--border-color);transition:background-color var(--transition-normal);background-color:#ffffffd9;position:sticky;top:0}[data-theme=dark] .site-header{background-color:#0f172ad9}.header-container{justify-content:space-between;align-items:center;height:4.25rem;display:flex}.logo-link{font-family:var(--font-heading);color:var(--text-primary);align-items:center;gap:.75rem;font-size:1.35rem;font-weight:800;display:flex}.logo-badge{background:var(--gradient-hero);color:#fff;border-radius:var(--radius-md);box-shadow:var(--shadow-sm);justify-content:center;align-items:center;padding:.4rem .65rem;font-size:1.1rem;display:flex}.nav-menu{align-items:center;gap:1.75rem;list-style:none;display:flex}.nav-link{color:var(--text-secondary);transition:color var(--transition-fast);font-size:.95rem;font-weight:600}.nav-link:hover{color:var(--primary)}.theme-toggle-btn{border-radius:var(--radius-full);background-color:var(--bg-tertiary);width:2.6rem;height:2.6rem;color:var(--text-primary);border:1px solid var(--border-color);transition:all var(--transition-normal);justify-content:center;align-items:center;display:flex}.theme-toggle-btn:hover{background-color:var(--border-color);transform:scale(1.05)}.hero-banner{text-align:center;background:radial-gradient(circle at 100% 0,#06b6d41f,#0000 45%),radial-gradient(circle at 0 100%,#0284c714,#0000 50%);padding:3rem 0 2rem}.hero-tag{border-radius:var(--radius-full);background-color:var(--primary-light);color:var(--primary);text-transform:uppercase;letter-spacing:.05em;border:1px solid #0284c733;align-items:center;gap:.5rem;margin-bottom:1.25rem;padding:.4rem 1rem;font-size:.85rem;font-weight:700;display:inline-flex}.hero-title{letter-spacing:-.02em;margin-bottom:1rem;font-size:clamp(2rem,4vw,3.25rem)}.hero-title span{background:var(--gradient-hero);-webkit-text-fill-color:transparent;-webkit-background-clip:text}.hero-subtitle{color:var(--text-secondary);max-width:680px;margin:0 auto 2.5rem;font-size:1.15rem}.calculator-section{padding-bottom:3.5rem}.calculator-card-wrapper{background-color:var(--bg-card);border-radius:var(--radius-xl);border:1px solid var(--border-color);box-shadow:var(--shadow-lg);grid-template-columns:1fr 340px;gap:2rem;padding:2rem;display:grid;position:relative;overflow:hidden}@media (width<=960px){.calculator-card-wrapper{grid-template-columns:1fr}}.calc-inputs-col{flex-direction:column;gap:1.75rem;display:flex}.input-card-box{background-color:var(--bg-tertiary);border-radius:var(--radius-lg);border:1px solid var(--border-color);padding:1.5rem}.input-label-row{justify-content:space-between;align-items:center;margin-bottom:1rem;display:flex}.input-title{align-items:center;gap:.5rem;font-size:1.1rem;font-weight:700;display:flex}.weight-display-badge{background-color:var(--bg-card);border:2px solid var(--primary);border-radius:var(--radius-md);box-shadow:var(--shadow-sm);align-items:baseline;gap:.25rem;padding:.35rem .85rem;display:flex}.weight-display-val{font-family:var(--font-heading);color:var(--primary);font-size:1.75rem;font-weight:800;line-height:1}.weight-display-unit{color:var(--text-secondary);font-size:1rem;font-weight:700}.slider-container{margin:1.25rem 0;position:relative}input[type=range]{-webkit-appearance:none;border-radius:var(--radius-full);background:var(--border-color);outline:none;width:100%;height:10px}input[type=range]::-webkit-slider-thumb{appearance:none;background:var(--gradient-hero);cursor:pointer;width:28px;height:28px;box-shadow:var(--shadow-md), 0 0 12px #0284c766;transition:transform var(--transition-fast);border:3px solid #fff;border-radius:50%}input[type=range]::-webkit-slider-thumb:hover{transform:scale(1.18)}.slider-ticks{color:var(--text-muted);justify-content:space-between;margin-top:.5rem;font-size:.8rem;font-weight:600;display:flex}.presets-label{text-transform:uppercase;color:var(--text-muted);letter-spacing:.04em;margin-bottom:.65rem;font-size:.85rem;font-weight:700}.weight-presets-grid{flex-wrap:wrap;gap:.5rem;display:flex}.preset-chip{border-radius:var(--radius-full);background-color:var(--bg-card);border:1px solid var(--border-color);color:var(--text-secondary);transition:all var(--transition-fast);padding:.4rem .85rem;font-size:.88rem;font-weight:600}.preset-chip:hover{border-color:var(--primary);color:var(--primary);transform:translateY(-1px)}.preset-chip.active{background-color:var(--primary);color:#fff;border-color:var(--primary);box-shadow:var(--shadow-sm)}.selectors-grid{grid-template-columns:1fr 1fr;gap:1.25rem;display:grid}@media (width<=640px){.selectors-grid{grid-template-columns:1fr}}.option-toggle-box{background-color:var(--bg-tertiary);border-radius:var(--radius-lg);border:1px solid var(--border-color);padding:1.25rem}.option-title{align-items:center;gap:.4rem;margin-bottom:.75rem;font-size:.95rem;font-weight:700;display:flex}.toggle-group{background-color:var(--bg-card);border-radius:var(--radius-md);border:1px solid var(--border-color);grid-template-columns:1fr 1fr;gap:.5rem;padding:.25rem;display:grid}.toggle-btn{border-radius:var(--radius-sm);color:var(--text-secondary);text-align:center;transition:all var(--transition-fast);padding:.6rem .5rem;font-size:.85rem;font-weight:700}.toggle-btn.active{background:var(--gradient-hero);color:#fff;box-shadow:var(--shadow-sm)}.calc-results-col{flex-direction:column;display:flex}.result-card{background:var(--gradient-hero);color:#fff;border-radius:var(--radius-lg);text-align:center;box-shadow:var(--shadow-glow);flex-direction:column;justify-content:space-between;align-items:center;height:100%;padding:2rem 1.5rem;display:flex;position:relative}.result-header{text-transform:uppercase;letter-spacing:.06em;opacity:.9;align-items:center;gap:.4rem;font-size:.9rem;font-weight:700;display:flex}.dose-number-wrapper{margin:1.25rem 0}.dose-large-val{font-family:var(--font-heading);text-shadow:0 2px 10px #00000026;font-size:clamp(3.2rem,5vw,4.2rem);font-weight:800;line-height:1}.dose-unit-tag{opacity:.95;font-size:1.4rem;font-weight:700}.dose-equivalence-list{-webkit-backdrop-filter:blur(8px);backdrop-filter:blur(8px);border-radius:var(--radius-md);background-color:#ffffff26;flex-direction:column;gap:.5rem;width:100%;margin-bottom:1.25rem;padding:1rem;display:flex}.eq-row{justify-content:space-between;align-items:center;font-size:.9rem;display:flex}.eq-label{opacity:.9}.eq-val{font-size:1.05rem;font-weight:800}.max-dose-notice{opacity:.85;border-radius:var(--radius-sm);background:#00000026;width:100%;margin-bottom:1.25rem;padding:.5rem .75rem;font-size:.8rem}.action-buttons-group{gap:.5rem;width:100%;display:flex}.btn-result-action{border-radius:var(--radius-md);color:var(--text-primary);transition:all var(--transition-fast);background-color:#fffffff2;flex:1;justify-content:center;align-items:center;gap:.4rem;padding:.75rem .5rem;font-size:.88rem;font-weight:700;display:inline-flex}.btn-result-action:hover{box-shadow:var(--shadow-md);background-color:#fff;transform:translateY(-2px)}.pipette-section-card{background-color:var(--bg-card);border-radius:var(--radius-xl);border:1px solid var(--border-color);box-shadow:var(--shadow-md);margin-bottom:2.5rem;padding:2rem}.section-title-wrapper{margin-bottom:1.5rem}.section-title-badge{color:var(--primary);background-color:var(--primary-light);border-radius:var(--radius-full);align-items:center;gap:.4rem;margin-bottom:.5rem;padding:.3rem .75rem;font-size:.85rem;font-weight:700;display:inline-flex}.section-h2{color:var(--text-primary);font-size:1.65rem}.pipette-grid{grid-template-columns:240px 1fr;align-items:center;gap:2rem;display:grid}@media (width<=768px){.pipette-grid{grid-template-columns:1fr}}.pipette-graphic-container{background-color:var(--bg-tertiary);border-radius:var(--radius-lg);justify-content:center;align-items:center;padding:1.5rem;display:flex}.pipette-svg{filter:drop-shadow(0 8px 16px #0000001a);width:140px;height:280px}.liquid-fill{transition:height .6s cubic-bezier(.34,1.56,.64,1),y .6s cubic-bezier(.34,1.56,.64,1)}.pipette-info-content{flex-direction:column;gap:1rem;display:flex}.pipette-status-box{background-color:var(--primary-light);border-left:4px solid var(--primary);border-radius:0 var(--radius-md) var(--radius-md) 0;padding:1rem 1.25rem}.pipette-status-text{color:var(--primary);font-size:1rem;font-weight:700}.pipette-tips-list{flex-direction:column;gap:.65rem;list-style:none;display:flex}.pipette-tips-list li{color:var(--text-secondary);align-items:flex-start;gap:.5rem;font-size:.95rem;display:flex}.schedule-card-wrapper{background-color:var(--bg-card);border-radius:var(--radius-xl);border:1px solid var(--border-color);box-shadow:var(--shadow-md);margin-bottom:2.5rem;padding:2rem}.time-picker-row{flex-wrap:wrap;align-items:center;gap:1rem;margin-bottom:1.5rem;display:flex}.time-input-custom{border-radius:var(--radius-md);border:1px solid var(--border-color);background-color:var(--bg-tertiary);color:var(--text-primary);padding:.6rem 1rem;font-size:1.1rem;font-weight:700}.timeline-flex-grid{grid-template-columns:repeat(auto-fit,minmax(140px,1fr));gap:1rem;display:grid}.schedule-item-card{background-color:var(--bg-tertiary);border-radius:var(--radius-lg);border:1px solid var(--border-color);text-align:center;transition:all var(--transition-fast);padding:1.25rem 1rem}.schedule-item-card.next-dose{border-color:var(--primary);background-color:var(--primary-light);box-shadow:var(--shadow-sm);transform:translateY(-2px)}.dose-number-badge{text-transform:uppercase;color:var(--text-muted);margin-bottom:.35rem;font-size:.75rem;font-weight:800}.schedule-time{font-family:var(--font-heading);color:var(--primary);font-size:1.5rem;font-weight:800}.schedule-dose-val{color:var(--text-secondary);font-size:.9rem;font-weight:700}.table-card-wrapper{background-color:var(--bg-card);border-radius:var(--radius-xl);border:1px solid var(--border-color);box-shadow:var(--shadow-md);margin-bottom:2.5rem;padding:2rem;overflow:hidden}.table-responsive-container{width:100%;margin-top:1.25rem;overflow-x:auto}.dosage-table{border-collapse:collapse;text-align:left;width:100%;font-size:.95rem}.dosage-table th{background-color:var(--bg-tertiary);color:var(--text-primary);border-bottom:2px solid var(--border-color);white-space:nowrap;padding:1rem;font-weight:700}.dosage-table td{border-bottom:1px solid var(--border-color);color:var(--text-secondary);padding:.9rem 1rem}.dosage-table tr:hover td{background-color:var(--bg-tertiary)}.dosage-table tr.row-highlight td{background-color:var(--primary-light);color:var(--primary);font-weight:700}.tag-table-accent{border-radius:var(--radius-sm);color:var(--primary);background-color:#0284c71a;padding:.2rem .5rem;font-size:.85rem;font-weight:700;display:inline-block}.guide-grid-container{grid-template-columns:1fr 1fr;gap:2rem;margin-bottom:2.5rem;display:grid}@media (width<=860px){.guide-grid-container{grid-template-columns:1fr}}.guide-box-card{background-color:var(--bg-card);border-radius:var(--radius-xl);border:1px solid var(--border-color);box-shadow:var(--shadow-md);padding:2rem}.formula-highlight-box{background:var(--bg-tertiary);border-radius:var(--radius-lg);color:var(--primary);text-align:center;border:1px dashed var(--primary);margin:1rem 0;padding:1.25rem;font-family:monospace;font-size:1.1rem;font-weight:700}.toxicology-alert-card{background-color:var(--danger-bg);border:1px solid var(--danger);border-radius:var(--radius-xl);justify-content:space-between;align-items:center;gap:1.5rem;margin-bottom:2.5rem;padding:1.75rem;display:flex}@media (width<=640px){.toxicology-alert-card{text-align:center;flex-direction:column}}.toxicology-info-text h3{color:var(--danger);margin-bottom:.25rem}.toxicology-info-text p{color:var(--text-secondary);font-size:.95rem}.btn-toxicology-call{background-color:var(--danger);color:#fff;border-radius:var(--radius-full);transition:transform var(--transition-fast);white-space:nowrap;align-items:center;gap:.5rem;padding:.75rem 1.5rem;font-size:1.05rem;font-weight:800;display:inline-flex;box-shadow:0 4px 12px #ef44444d}.btn-toxicology-call:hover{color:#fff;transform:scale(1.05)}.faq-section-wrapper{margin-bottom:3.5rem}.faq-accordion-list{flex-direction:column;gap:1rem;margin-top:1.5rem;display:flex}.faq-item-card{background-color:var(--bg-card);border-radius:var(--radius-lg);border:1px solid var(--border-color);box-shadow:var(--shadow-sm);transition:border-color var(--transition-fast);overflow:hidden}.faq-item-card.open{border-color:var(--primary)}.faq-question-btn{width:100%;color:var(--text-primary);text-align:left;justify-content:space-between;align-items:center;padding:1.25rem 1.5rem;font-size:1.05rem;font-weight:700;display:flex}.faq-answer-content{color:var(--text-secondary);padding:0 1.5rem 1.25rem;font-size:.95rem;line-height:1.6}.volumecylinder-footer{color:#94a3b8!important;background:linear-gradient(#0b1120 0%,#030712 100%)!important;border-top:1px solid #ffffff14!important;padding:4rem 0 2rem!important}.footer-v2-grid{grid-template-columns:2fr 1fr 1.5fr 2fr;gap:2.5rem;margin-bottom:3rem;display:grid}@media (width<=960px){.footer-v2-grid{grid-template-columns:1fr 1fr}}@media (width<=580px){.footer-v2-grid{grid-template-columns:1fr}}.footer-brand-tagline{color:#94a3b8;margin-bottom:1.25rem;font-size:.9rem;line-height:1.6}.footer-social-row{gap:.65rem;display:flex}.social-pill-btn{color:#cbd5e1;width:2.5rem;height:2.5rem;transition:all var(--transition-fast);background-color:#ffffff0d;border:1px solid #ffffff1a;border-radius:10px;justify-content:center;align-items:center;display:inline-flex}.social-pill-btn:hover{background-color:var(--primary);border-color:var(--primary);color:#fff;transform:translateY(-2px)}.footer-col-title{letter-spacing:.12em;color:#fff;text-transform:uppercase;margin-bottom:1.25rem;font-size:.85rem;font-weight:800}.footer-links-list{flex-direction:column;gap:.65rem;list-style:none;display:flex}.footer-modal-link{color:#94a3b8;transition:color var(--transition-fast);text-align:left;font-size:.9rem}.footer-modal-link:hover{color:#fff}.contact-info-list{flex-direction:column;gap:.85rem;display:flex}.contact-item-row{color:#06b6d4;transition:color var(--transition-fast);align-items:center;gap:.65rem;font-size:.9rem;display:flex}.contact-item-row:hover{color:#38bdf8}.language-grid-box{grid-template-columns:repeat(5,1fr);gap:.45rem;display:grid}.lang-pill-btn{color:#94a3b8;text-align:center;transition:all var(--transition-fast);background:#ffffff0a;border:1px solid #ffffff1a;border-radius:6px;padding:.35rem .2rem;font-size:.78rem;font-weight:700}.lang-pill-btn:hover{color:#fff;background:#06b6d41a;border-color:#06b6d4}.lang-pill-btn.active{color:#06b6d4;background:#06b6d426;border-color:#06b6d4;box-shadow:0 0 10px #06b6d440}.footer-bottom-bar-v2{color:#64748b;border-top:1px solid #ffffff14;justify-content:space-between;align-items:center;padding-top:1.75rem;font-size:.85rem;display:flex}.btn-back-to-top{color:#06b6d4;transition:color var(--transition-fast);align-items:center;gap:.3rem;font-weight:700;display:inline-flex}.btn-back-to-top:hover{color:#38bdf8}.modal-overlay{-webkit-backdrop-filter:blur(6px);backdrop-filter:blur(6px);z-index:1000;background:#000000bf;justify-content:center;align-items:center;padding:1rem;display:flex;position:fixed;inset:0}.modal-content-box{background-color:var(--bg-card);color:var(--text-primary);border-radius:var(--radius-xl);border:1px solid var(--border-color);width:100%;max-width:500px;box-shadow:var(--shadow-lg);padding:2rem;position:relative}.modal-close-btn{color:var(--text-muted);transition:color var(--transition-fast);border-radius:50%;padding:.25rem;position:absolute;top:1rem;right:1rem}.modal-close-btn:hover{color:var(--text-primary)}@media print{.site-header,.theme-toggle-btn,.action-buttons-group,.faq-section-wrapper,.site-footer{display:none!important}body{color:#000!important;background:#fff!important}.calculator-card-wrapper{box-shadow:none!important;border:2px solid #000!important}}